Biofortification is the process of increasing the density of vitamins and minerals in a crop, through plant breeding or agronomic practices, so that when consumed regularly will generate measurable improvement in vitamin and mineral nutritional status. We are conducting two large randomized controlled trials in the urban slums of Mumbai to assess the efficacy of biofortification as a strategy to improve nutritional status, and immune and cognitive functioning in infants.
Pearl Millet Trial
The first trial focuses on children 12-18 months of age and a high iron- and zinc-variety of pearl millet. This feeding trial will continue for 9 months and examine the impact of biofortified pearl millet-based complementary food on iron and zinc status, growth, and immune and cognitive function.
ClinicalTrials.gov ID: NCT02233764
Supported by two competitive research grants from:
Multiple Biofortified Food Crops Trial
The second trial expands the crop portfolio to include orange-fleshed sweet potatoes, wheat, and lentils, in addition to pearl millet to deliver 50-70% of the estimated average requirements for vitamin A, iron, and zinc to breastfeeding mothers and their 6-12 months old infants.
ClinicalTrials.gov ID: NCT02648893
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